![]() Scientists believe that piriformis syndrome causes only about 0.3% to 6% of lower back pain. It’s the longest, largest nerve in your body. The nerve travels from your spinal cord, through your buttocks, down the back of each leg, to your feet. The sciatic nerve most commonly runs underneath the piriformis. Your piriformis muscle extends to each side of your body and aids in almost every movement of your lower body. It runs from your lower spine through your butt to the top of your thighs. It can happen on one side of your body or both. It can cause pain or numbness in your buttock and down the back of your leg. Piriformis syndrome occurs when your piriformis muscle compresses your sciatic nerve and results in inflammation. ![]() ![]() Piriformis syndrome is caused by your piriformis muscle pressing on the sciatic nerve that runs underneath it.
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